Oxidative stress markers in Thoroughbred horses after castration surgery under inhalation anesthesia

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Oxidative stress markers in Thoroughbred horses after castration surgery under inhalation anesthesia

Oxidative stress has been reported to occur during surgery. It is important to reduce intraoperative oxidative stress to improve the postoperative prognosis. However, there are no reports regarding oxidative stress related to surgery in horses. In the present study, we measured pre and postsurgical diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP); the oxid...

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NOTE Surgery Clinical Evaluation of Total Intravenous Anesthesia Using a Combination of Propofol and Medetomidine following Anesthesia Induction with Medetomidine, Guaifenesin and Propofol for Castration in Thoroughbred Horses

Seven Thoroughbred horses were castrated under total intravenous anesthesia (TIVA) using propofol and medetomidine. After premedication with medetomidine (5.0 g/kg, intravenously), anesthesia was induced with guaifenesin (100 mg/kg, intravenously) and propofol (3.0 mg/kg, intravenously) and maintained with constant rate infusions of medetomidine (0.05 g/kg/min) and propofol (0.1 mg/kg/min). Q...

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Evaluation of total intravenous anesthesia with propofol-guaifenesin-medetomidine and alfaxalone-guaifenesin-medetomidine in Thoroughbred horses undergoing castration

Anesthetic and cardiorespiratory effects of total intravenous anesthesia (TIVA) technique using propofol-guaifenesin-medetomidine (PGM) and alfaxalone-guaifenesin-medetomidine (AGM) were preliminarily evaluated in Thoroughbred horses undergoing castration. Twelve male Thoroughbred horses were assigned randomly into two groups. After premedication with intravenous (IV) administrations of medetom...

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Response to Oxidative Stress during Surgery under Ketamine/Propofol Anaesthesia in Acepromazine-Xylazine Premedicated Horses

The study was conducted in twelve clinical cases of horses undergoing diagnostic and surgical procedures warranting general anaesthesia. The cases were randomly divided into two groups: group I and group II, each consisting of six horses. Preanaesthetic medication done with Xylazine hydrochloride @ 0.5mg/kg and Acepromazine maleate @0.03 mg/kg body weight in both the groups. Ketamine @ 2.20 mg/...

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Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise

Upon intensive, exhaustive exercise, exercise-induced reactive oxygen species may exceed the antioxidant defence threshold, consequently resulting in muscular damage or late-onset chronic inflammation. Recently, the therapeutic antioxidant and anti-inflammatory effects of molecular hydrogen (H2) for human rheumatoid arthritis have been demonstrated. However, it is also important to clarify the ...

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ژورنال

عنوان ژورنال: Journal of Equine Science

سال: 2016

ISSN: 1340-3516,1347-7501

DOI: 10.1294/jes.27.77